Raw Material Testing: Identity, Purity & Potency Verification
Verify every incoming ingredient before it enters your production line. HPLC, FTIR, and ICP-MS methods. Signed CoA included.
Ayah Labs tests raw materials for identity, purity, and potency using validated HPLC, FTIR, and ICP-MS methods. We provide a signed Certificate of Analysis for every batch, ensuring your ingredients meet USP and FDA 21 CFR Part 111 specifications.
Raw material testing is the first and most critical line of defense in supplement and cosmetic manufacturing. Before any ingredient enters your production line, it must be verified for identity, purity, and potency. Adulterated or misidentified raw materials are a leading cause of product recalls, regulatory action, and consumer harm. Ayah Labs provides comprehensive incoming material testing using validated analytical methods including HPLC, FTIR spectroscopy, and ICP-MS elemental analysis.
Why Raw Material Testing Is Non-Negotiable
FDA 21 CFR Part 111 requires dietary supplement manufacturers to test every incoming raw material for identity and to establish specifications for purity and potency. Failing to test incoming materials is one of the most common FDA 483 observations. Beyond regulatory compliance, raw material fraud — including adulteration, substitution, and mislabeling — is widespread in the global ingredient supply chain. Independent third-party testing by a qualified contract laboratory is the only way to verify that what your supplier says is in the bag is actually what you received.
Our Testing Methods
We use HPLC (High-Performance Liquid Chromatography) for potency and identity testing of active compounds, FTIR (Fourier Transform Infrared Spectroscopy) for rapid identity confirmation, and ICP-MS (Inductively Coupled Plasma Mass Spectrometry) for elemental analysis and heavy metal screening. All methods are validated and traceable to USP reference standards. Results are delivered with a signed Certificate of Analysis that includes method references, acceptance criteria, and pass/fail determinations.
Supplier Qualification Support
Raw material testing is also a key component of supplier qualification programs. Ayah Labs can provide ongoing testing programs for approved supplier lists, helping you build a defensible quality system. We work with supplement manufacturers, cosmetic brands, and contract manufacturers to establish incoming material specifications, test frequency schedules, and out-of-specification (OOS) investigation protocols.
Tests & Methods Included
- ✓ Identity testing by FTIR spectroscopy
- ✓ Potency and assay by HPLC
- ✓ Heavy metal screening by ICP-MS
- ✓ Moisture and loss on drying
- ✓ Microbial limits (USP <61>/<62>)
- ✓ Residual solvents
- ✓ Particle size distribution
- ✓ Appearance and organoleptic evaluation
- ✓ pH and specific gravity
- ✓ Adulteration screening
Regulatory Standards & Compliance
- USP
- FDA 21 CFR Part 111
- ISO 17025 Aligned
- GMP
Industries We Serve
- Supplement Manufacturers
- Cosmetic Brands
- Contract Manufacturers
- Raw Material Suppliers
- Private Label Brands
Request a Quote
Pricing depends on your product and test requirements. Tell us what you need and we will email a detailed quote within 24 hours.
Get a Quote →Frequently Asked Questions
What raw materials do you test?
We test botanical extracts, vitamins, minerals, amino acids, proteins, lipids, excipients, and cosmetic raw materials including active ingredients, emollients, and preservatives. If you have a specific material not listed, contact us — we can discuss custom testing options.
How much sample do I need to send for raw material testing?
Sample requirements vary by test. For most identity and potency tests, 5–20 grams is sufficient. For a full panel including microbiology and heavy metals, plan for 50–100 grams. We will confirm exact requirements when you submit your test request.
How long does raw material testing take?
Standard turnaround is 48–72 hours for most identity and chemistry tests. Microbiology testing requires 5–7 business days due to incubation requirements. Rush turnaround is available for select tests — contact us to discuss your timeline.
Why manufacturers choose Ayah Labs for raw material testing
Fast turnaround
Signed CoA in 48–72 hours
Direct scientist access
Talk to the scientist running your tests
No minimums
1 SKU or 100 — same quality
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